The Spitzer Infrared Nearby Galaxy Survey is a comprehensive infrared imaging and spectroscopic survey of 75 nearby galaxies. Its primary goal is to characterize the infrared emission of galaxies and their principal infrared-emitting components, across a broad range of galaxy properties and star formation environments. SINGS provides new insights into the physical processes connecting star formation to the interstellar medium properties of galaxies and provides a vital foundation for understanding infrared observations of the distant universe and ultraluminous and active galaxies.